MR-derived concentration of Gd-Albumin compared with predicted porous media transport profiles at time = 30 and 91 min. Concentration was normalized by dividing by the maximum MR-derived concentration, 6.4 mg/mL. Deff = 7.12 and 5.0 (10-11 m2/s) were experimentally measured at temperatures 37 and 25°C, respectively, by Liang et al. [29]. Deff = 6.75 (10-11 m2/s) was the optimal diffusivity obtained in this study. For Deff = 7.12, 6.75, and 5.0 (10-11 m2/s), R2 = 0.91, 0.91, and 0.84 for t = 91 min, and 0.91, 0.92, and 0.92 for t = 30 min, respectively.