Table 1. Blinded drug-resistance testing with the 50 µM screening format after virus enrichment by ultracentrifugation.
3TC | NVP | |||||
Genotype | Wild type | Mixed genotype | Mutanta | Wild type | Mixed genotype | Mutantb |
Amp-RT sensitive | 94 | 3 | 2 | 73 | 7 | 2 |
Amp-RT resistant | 4 | 5 | 65 | 3 | 11 | 77 |
Total | 98 | 8 | 67 | 76 | 18 | 79 |
including the mutations M184V/I.
including the mutations K103N, Y181C/I, Y188L, G190A/Q, or K238N.