Table 1. Within-group brain activation to food versus non-food images in, women with AN and the subtypes, BN and HC.
Brain Regions | BA | Laterality | x | y | z | Cluster size (voxels) | Cluster-p |
Food > Non-Food | |||||||
AN (n = 18) | |||||||
Cerebellum | --- | L | −18 | −74 | −23 | 443 | 0.0002 |
DLPFC | 9 | R | 47 | 7 | 30 | 74 | 0.001 |
Precuneus | 39 | R | 40 | −63 | 33 | 119 | 0.002 |
RAN (n = 11) | |||||||
Cerebellum | -- | L | −25 | −67 | −23 | 41 | 0.001 |
Visual Cortex | 18 | L | −14 | −85 | −13 | 50 | 0.001 |
DLPFC | 9 | R | 40 | 4 | 26 | 66 | 0.002 |
Precuneus | 7 | --- | 0 | 41 | 46 | 179 | 0.0006 |
BPAN (n = 7) | |||||||
Cerebellum | --- | L | −4 | −56 | −36 | 111 | 0.0008 |
Cerebellum | --- | R | 25 | −63 | −20 | 389 | 0.0002 |
SMA | 6 | R | 22 | −4 | 53 | 124 | 0.0009 |
BN (n = 8) | |||||||
Visual Cortex | 18 | R | 11 | −81 | −4 | 1416 | 0.01 |
DLPFC | 9 | L | −33 | −30 | 28 | 154 | 0.01 |
Insular Cortex | 13 | R | −46 | 10 | −4 | 168 | 0.01 |
Precentral Gyrus | 3 | L | −54 | −15 | 28 | 2774 | 0.01 |
HC (n = 24) | |||||||
Cerebellum | --- | L | −4 | −63 | −20 | 497 | 0.0002 |
STG | 22 | R | 51 | −11 | −7 | 300 | 0.0002 |
MTG | 22 | R | 51 | −37 | 7 | 78 | 0.002 |
Caudate | --- | L | −4 | 0 | 20 | 236 | 0.0003 |
Talairach Coordinates = x, Saggital plane, y, Coronal plane, z, Axial plane; Cluster size in voxels, each voxel equals 3.75mm×3.75 mm×3 mm; Cluster p = cluster probability corrected at the level of one false positive or less. ABBREVIATIONS: BA = Brodmann's Area; Laterality = L, Left, R, Right; p = probability; AN = Anorexia Nervosa, RAN = Restricting Anorexia Nervosa, BPAN = Binge Purge Anorexia Nervosa, BN = Bulimia Nervosa, HC = Healthy Controls; DLPFC = Dorsolateral Prefrontal Cortex, SMA = Supplementary Motor Area; STG = Superior Temporal Gyrus, MTG = Middle Temporal Gyrus.