Table 1. Statistical analysis of mutant allele/genotype in our case-control study.
Group (N) | Parameter | C | T | CC | CT | TT | CT+TT |
Controls (315) | N (%) | 560 (88.9) | 70 (11.1) | 251 (79.6) | 58 (18.4) | 6 (1.9) | 64 (20.31) |
Azoo$ (68) | N (%) | 113 (83.1) | 23 (16.9) | 49 (72.1) | 15 (22.1) | 4 (5.9) | 19 (27.9) |
OR/95% CI | 1.63 (0.98–2.72)# | 1.33 (0.70–2.53) | 3.42 (0.93–12.55) | 1.52 (0.84–2.76) | |||
p-value/Chi-square | 0.06/.53 | 0.39/0.73 | 0.07/- | 0.17/1.91 | |||
Astheno (135) | N (%) | 229 (84.8) | 41 (15.2) | 103 (76.3) | 23 (17.03) | 9 (6.67) | 32 (23.7) |
OR/95% CI | 1.43 (0.95–2.17) | 0.97 (0.57–1.65) | 3.66 (1.27–10.53) | 1.22 (0.75–1.97) | |||
p-value/Chi-square | 0.09/2.9 | 0.89/0.02 | 0.02*/- | 0.42/0.65 | |||
Normo (141) | N (%) | 246 (87.2) | 36 (12.8) | 110 (78) | 26 (18.45) | 5 (3.5) | 31 (22) |
OR/95% CI | 1.17 (0.76–1.80) | 1.02 (0.61–1.71) | 1.90 (0.57–6.36) | 1.11 (0.68–1.79) | |||
p-value/Chi-square | 0.47/0.52 | 0.92/0.01 | 0.33/- | 0.69/0.16 | |||
OAT (65) | N (%) | 105 (80.7) | 25 (19.3) | 41 (63.1) | 23 (35.4) | 1 (1.5) | 24 (37) |
OR/95% CI | 1.90 (1.15–3.15) | 2.43 (1.35–4.36) | 1.02 (0.12–8.70) | 2.30 (1.29–4.07) | |||
p-value/Chi-square | 0.01*/6.5 | 0.002*/9.19 | 1.00/- | 0.00385*/8.35 | |||
Uncateg (113) | N (%) | 179 (79.2) | 47 (20.8) | 75 (66.4) | 29 (25.7) | 9 (7.96) | 38 (33.6) |
OR/95% CI | 2.10 (1.40–3.15) | 1.67 (1.00–2.80) | 5.02 (1.73–14.56) | 1.99 (1.23–3.20) | |||
p-value/Chi-square | 0.0002*/13.22 | 0.0485*/3.89 | 0.003*/- | 0.004*/8.12 | |||
Total (522) | N (%) | 872 (83.5) | 172 (16.5) | 378 (72.4) | 116 (22.2) | 28 (5.4) | 144(27.6) |
OR/95% CI | 1.578 (1.17–2.13) | 1.33 (0.93–1.89) | 3.10 (1.27–7.60) | 1.49 (1.07–2.09) | |||
p-value/Chi-square | 0.0025*/9.14 | 0.12/2.49 | 0.0095*/6.73 | 0.0187*/5.56 |
The calculations for mutant allele have been done with reference to allele ‘C’; for mutant genotypes with reference to ‘CC’ between cases and controls.
Azoo-azoospermia; Astheno-asthenozoospermia; Normo-normozoospermia; OAT-oligoasthenoteratozoospermia; Uncateg: uncategorized.
*Indicates statistically significant value.