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. 2011 Jul 20;6(7):e22526. doi: 10.1371/journal.pone.0022526

Figure 5. The effect of distinct met-RANTES doses treatment in the control of A. actinomycetemcomitans infection.

Figure 5

C57Bl/6 mice were infected orally with AA, treated with met-RANTES at 0.5 and 5 mg doses or (V) veicule, (-) non treated and (C) control non-infected mice, sacrificed at day 30 post-infection and evaluated for: A) levels of myeloperoxidase (MPO) in periodontal tissues; B) levels of inducible nitric oxide syntase (iNOS) expression; C) levels of Aa-specific IgG; and D) levels of C reactive protein (CRP) in serum; all performed as described in Material and methods. Different italic low case letters represent statistically significant differences among the doses in the same experimental group (P<0.05; One-way ANOVA).