Table 4.

Mean cord blood cytokine concentrations in preterm births with and without placental inflammation

	n	Mean ± SD **	Crude		Adjusted *
			ß (SE)	p	ß (SE)	p
Log(IL1β)
No Inflammation	133	41.5 ± 29.9	Ref		Ref
Inflammation	67	134 ± 295.6	0.634(0.144)	<0.0001	0.571(0.162)	0.0004
Log(IL6)
No Inflammation	133	143.3 ± 590.6	Ref		Ref
Inflammation	67	1292.8 ± 1722.2	1.887(0.259)	<0.0001	1.687(0.286)	<0.0001
Log(IL8)
No Inflammation	133	46.3 ± 79.3	Ref		Ref
Inflammation	67	698.4 ± 1166.8	1.905(0.221)	<0.0001	1.699(0.241)	<0.0001
Log(IL4)
No Inflammation	133	7 ± 5.2	Ref		Ref
Inflammation	67	8.1 ± 11.7	-0.097(0.105)	0.355	-0.033(0.118)	0.777
Log(IL10)
No Inflammation	133	501.7 ± 401.4	Ref		Ref
Inflammation	67	584.3 ± 697.4	-0.318(0.279)	0.254	-0.68(0.308)	0.027
Log(TGFβ)
No Inflammation	133	160 ± 115.7	Ref		Ref
Inflammation	67	128.2 ± 116.7	-0.331(0.134)	0.014	-0.307(0.151)	0.042
Log(BDNF)
No Inflammation	133	2433.9 ± 2268.3	Ref		Ref
Inflammation	67	2029 ± 2349.8	-0.366(0.148)	0.013	-0.234(0.165)	0.155
Log(NT3)
No Inflammation	133	164.2 ± 253.7	Ref		Ref
Inflammation	67	89.9 ± 123.8	-0.866(0.232)	0.0002	-0.884(0.26)	0.0007
Log(NT4)
No Inflammation	133	24.5 ± 14	Ref		Ref
Inflammation	67	27 ± 27.2	-0.046(0.112)	0.682	0.001(0.126)	0.995

^*Adjusted for 1 minute Apgar ≤ 3, gestational age and steroid exposure.

^**Mean ± SD for original cytokine concentration prior to log transformation for modeling.