Table 1.
Characteristics of patients admitted for ischemic stroke stratified by history of hypertension (percent shown unless otherwise indicated)
| Full cohort N=3640 |
HTN History N=2877 (79%) |
No HTN History N= 763 (21%) |
|
|---|---|---|---|
| Gender (%) | |||
| Males | 97.7 | 98.0 | 96.7 |
| Age (%) | |||
| <65 | 46.9 | 45.4 | 52.4 |
| 65– 74 | 22.4 | 23.8 | 17.2 |
| 75+ | 30.7 | 30.8 | 30.4 |
| Race (%) | |||
| White | 62.7 | 61.3 | 68.0 |
| Black | 23.5 | 24.8 | 18.4 |
| Other | 6.8 | 6.8 | 6.4 |
| Missing race | 7.1 | 7.1 | 7.2 |
| NIH stroke scale (%) | |||
| 0–2 | 50.9 | 50.4 | 52.8 |
| 3–9 | 40.0 | 40.5 | 38.3 |
| 10 + | 9.0 | 9.1 | 8.9 |
| Weight available (%) | 81.0 | 80.0 | 84.7 |
| Weight (median IQR) | 185 (159 – 214) | 187 (162 – 217) | 174 (149 – 201) |
| Current Smoker (%) | 35.9 | 34.3 | 42.1 |
| Charlson Score (mean ±SD) | 4.7 ± 2.0 | 4.8 ± 1.9 | 4.4 ± 2.1 |
| Number of Co morbidities at admission (mean ±SD) | 3.5 ± 2.1 | 3.9 ± 2.0 | 2.0 ±1.8 |
| Co morbidities (%) | |||
| Cerebrovascular disease* | 28.8 | 31.3 | 19.1 |
| Cardiovascular disease† | 36.8 | 39.1 | 27.8 |
| Atrial Fibrillation | 15.2 | 16.2 | 11.5 |
| Diabetes | 40.1 | 44.8 | 22.4 |
| Hyperlipidemia | 48.7 | 53.8 | 29.6 |
| Renal disease | 1.1 | 1.2 | 0.5 |
| Liver disease | 2.0 | 1.9 | 2.0 |
| HIV | 0.8 | 0.7 | 1.2 |
| Cancer‡ | 7.3 | 7.0 | 8.7 |
| Pulmonary disease | 15.7 | 15.2 | 17.4 |
| Use of antipsychotic medication‖ | 5.3 | 5.2 | 5.8 |
| Depression | 16.8 | 17.0 | 16.4 |
| Dementia | 7.3 | 7.6 | 6.2 |
| Peptic Ulcer disease | 1.6 | 1.5 | 2.1 |
| Rheumatologic Disorders§ | 0.5 | 0.6 | 0.4 |
| N medications at admission (mean ±SD) | 7.1 ± 4.9 | 7.6 ± 4.8 | 5.4 ± 4.9 |
| Discharged to home (%) | 67.5 | 67.5 | 67.8 |
Cerebrovascular disease includes carotid endarterectomy, carotid stent, ischemic stroke or TIA
Cardiovascular disease includes history of coronary artery disease, acute myocardial infarction, coronary artery bypass, percutaneous transluminal coronary angioplasty with or without stent placement or any history of peripheral vascular disease
Cancer includes any diagnosis of leukemia, lymphoma, or any solid tumor in past 5 years, metastatic tumor, or multiple myeloma
Antipsychotics include chlorpromazine; fluphenazine; thioridizine: trifluoroperazine; thiothixene; aripiprazole; clozapine: haloperidol; loxapine: molindone; olanzapine: quetiapine: risperidone; ziprasidone
Rheumatologic disorders include Lupus and any vasculitis