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Effects of treatments on proteinuria onset and survival. Proteinuria (A) and survival (B) of Ad-IFNα treated NZB/W F1 mice. p values against Ad-IFNα treated controls: p = 0.0005 (proteinuria) and p = 0.0077 (survival), TACI-Ig treated mice; p = 0.0555 (proteinuria) and p = 0.0483 (survival), low dose CTLA4Ig treated mice; p<0.0001 (proteinuria and survival), high dose CTLA4Ig treated mice. Data are pooled from two representative experiments with a total of 15–27 mice per group.
