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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: J Immunol. 2011 Jun 24;187(3):1506–1513. doi: 10.4049/jimmunol.1004142

Figure 4.

Figure 4

Effects of treatments on renal IgG deposition and damage. A: renal glomerular damage (filled circles) and interstitial inflammation (open circles) in different groups of mice. The mice with >300mg/dl proteinuria that died before tissue could be harvested were assigned a histological score of 4 for statistical analysis. p values are compared with Ad-IFNα treated controls. Horizontal bars represent median score. *: p < 0.05, †: p < 0.01. B: renal immunofluorescence staining with anti-IgG2a (upper) and anti-IgG3 (lower), 10X magnification. Results of high dose CTLA4Ig treated mice are variable and not shown (see text). Data are representative of two experiments with 4–5 mice per group.