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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: J Immunol. 2011 Jun 24;187(3):1506–1513. doi: 10.4049/jimmunol.1004142

Figure 7.

Figure 7

Effects of triple therapy on germinal centers and autoantibody production. The numbers of total (A) or anti-dsDNA (B) IgG or IgM producing plasma cells per spleen from different groups of mice were determined by ELISpot assay. p values are compared with Ad-IFNα only controls. Median + interquartile range shown *: p < 0.05, **: p < 0.02, †: p < 0.01. Data are pooled from three representative experiments with a total of 15–34 mice per group. C: immunofluorescence staining of spleens (upper and middle - 5X magnification) or kidneys (lower–10X magnification) with anti-IgD (red) and peanut agglutinin (green; upper), or anti-IgG2a (green; middle and lower). Results of anti-CD40L treated mice are variable and not shown. Data are representative of 5–6 mice per group.