Table 4.
Results of longitudinal models of cognitive function among participants free of MCI at baseline.
3MSE | ADAS-cog | |||
---|---|---|---|---|
Exposure | Slope1 (95% CI) | p- value2 |
Slope 1 (95% CI) | p- value2 |
No LLM Statin ever Other LLM ever |
−0.11 (−0.15, − 0.07) −0.06 (−.10, −.01) −0.16 (−0.29, − 0.04) |
.066 .43 |
0.05 (0.02, 0.07) 0.015 (−0.01, 0.04) −0.03 (−0.11, − 0.04) |
.058 .041 |
Statin use None Former Current |
−0.14 (−0.18, − 0.10) − 0.06 (−0.18, 0.07) −0.07 (−0.12, − 0.02) |
.19 .014 |
0.04 (0.02, 0.07) 0.03(−0.05, 0.11) 0.01 (−0.02, 0.04) |
.73 .045 |
Type of statin (ever use) None Lipophilic Nonlipophilic |
−0.10 (−0.14, − 0.06) −0.06 (−0.11, − 0.01) −0.16 (−0.26, − 0.06) |
.13 .26 |
0.04 (0.02, 0.06) 0.01 (−0.02, 0.03) 0.05 (−0.00, 0.11) |
.044 .66 |
Estimate of rate of change at midpoint of follow-up time.
Test for difference in slope compared to non-users.