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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: J Vasc Surg. 2011 Apr 16;54(2):489–496. doi: 10.1016/j.jvs.2011.01.043

Fig. 2.

Fig. 2

Effect of escin and diosmin on rat IVC. Rat IVC segments were treated with increasing concentrations (10−10 to 10−4 M) of escin (A) or diosmin (B) in normal Krebs (2.5 mM Ca2+), in the presence of diltiazem (10−5 M), and in Ca2+-free (2 mM EGTA) Krebs. In other experiments, IVC segments incubated in 0 Ca2+ Krebs were either nontreated (control) or treated with 10−4 M escin (C) or diosmin (D) then increasing concentrations of extracellular CaCl2 (0.1 to 2.5 mM) were added and the Ca2+ concentration-contraction curve was constructed. Data represent the means±SEM (n=4 to 9).