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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: J Tissue Eng Regen Med. 2011 May 23;5(8):e228–e238. doi: 10.1002/term.429

Figure 2.

Figure 2

TEM (31 000×) showing cell-matrix interaction and matrix condition. A) Control, B) TGF-β1 treated (T1), C) TGF-β2 treated (T2), and D) TGF-β3 treated (T3) constructs. The fibril orientation changes direction more than once in all conditions. T3 treated construct (D) shows higher density of collagen fibril and ECM alignment compared to controls, T1 and T2. T3 also appeared to show fewer cells with actin stress fibers (data not shown). E) Example of cell with vesicles (arrows) correlating with actin filaments (arrowhead). White “C” = cell and “F” = fibrils. Bars = 500nm.