Figure 5. PDL1: B7.1 blockade upregulates production of Th1, Th2 and proinflammatory cytokines in B6 recipients of bm12 hearts.

IFN-γ (A), IL-4 (B) and IL-6 (C) production by the splenocytes from B6 recipients of bm12 heart grafts assessed at 10 days post-Tx by ELISPOT. Data represent mean ± SEM of triplicate wells from three mice per group.