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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Am J Med Genet A. 2011 Jul 7;155(8):2008–2010. doi: 10.1002/ajmg.a.34022

TABLE I.

Cases of Likely Monozygotic Twins with Van der Woude Syndrome in the Literature

Zygosity/ Zygosity Testing Presentation
Cervenka et al, 1967 Monozygotic/ Zygosity determined by examination of features and blood group Lip pits in both, CL in one
Hersh and Verdi, 1992 Monozygotic/ DNA linkage analysis Unilateral CL/P, lip pits and natal tooth in both
Kondo et al., 2002 Monozygotic/ Tested with microsatellite markers One twin with the condition due to a new mutation, one twin without the mutation
Tokat et al., 2005 Monozygotic/ No information on testing Lip pits in both, CL in one, CP in one
Vignale et al., 1998 Unknown Unilateral CL and lip pits in both