Table 1.
Characteristics of the PDAC cell lines in the metastasis model
Panc-1 | MiaPaCa-2 | BxPC-3 | ||||
---|---|---|---|---|---|---|
Classifications | Value | Percent | Value | Percent | Value | Percent |
Mice injected | 17 | 17 | 15 (13)a | |||
Mice that formed tumorsb | 12 | 71% | 15 | 88% | 12 | 92% |
Mice autopsied | 12 | 71% | 13 | 76% | 9 | 69% |
Mice autopsied with tumors | 9 | 75% | 11 | 85% | 9 | 100% |
TO tumorsc | 2 | 22% | 1 | 8% | 6 | 67% |
T+ tumorsc | 1 | 11% | 2 | 18% | 0 | 0% |
ET tumorsc | 6 | 67% | 8 | 73% | 3 | 33% |
Two mice died shortly after injection, likely due to embolism, therefore they are excluded from subsequent calculations
As determined by BLI
Numbers and percentages for these tumors are based on analyses of the autopsied mice with tumors
TO = Thoracic only tumors
T+ = Thoracic + systemic tumors
ET = Extrathoracic (systemic) tumors