Table 1.

Functional attributes of evolutionary classes.

Analysis	Uniform	Multiarch	Multipar	Complexarch
Fraction of yeast proteins that participate in complexes (%)	7.78*	8.39*	5.85§	6.36
Fraction of essential yeast proteins (%)	19.79*	25.2*	10.51§	14.44
Average number of domains in a protein (including repetitives)	1.2	2.46	1.22	2.37
Average number of domains (counting only unique domains)	1.14	1.57	1.15	1.73
Fraction of fungi-specific domains (%)	5.23*	1.68§	3.9	4.38*
Fraction of ancient clusters (%)	62.14§	73.73*	75.5*	83.71*
Mean degree in S. cerevisiae protein-protein interaction network	11.12§	15.2	13.93	15.18
Mean clustering coefficient in S. cerevisiae protein-protein interaction network	0.154*	0.156*	0.102§	0.116

^*significantly high (hypergeometric score, p-value < 0.05)

^§significantly low (hypergeometric score, p-value < 0.05)