Table 1.
Formulations studied
| Liposomes | Formulation (mol%) | Naming convention for radiolabeled liposomes |
|||||
|---|---|---|---|---|---|---|---|
| a. HSPC |
b. DSPE- PEG2k- OMe |
c. Cholesterol |
d. DSPE- maleimide (MI) |
e. DPPE- maleimide |
f. DPPC |
||
| Long circulating | 56 | 5 | 39 | - | - | - | |
| 1 mol% DSPE-MIa | 55 | 5 | 39 | 1 | - | - | 64Cu-DSPE liposomes |
| 1 mol% DPPE-MIb | 55 | 5 | 39 | - | 1 | - | 64Cu-DPPE liposomes |
| 1 mol% DSPE-MI with 1mol% DPPCc |
54 | 5 | 39 | 1 | - | 1 |
64Cu-DSPE-1mol% DPPC liposomes |
a
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(3-maleimidopropylamide)
b
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide]
c
1,2-dipalmitoyl-sn-glycero-3-phosphocholine