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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: J Chem Neuroanat. 2011 Jun 6;41(4):200–218. doi: 10.1016/j.jchemneu.2011.05.010

Figure 7.

Figure 7

Histograms illustrating the average positive pixels and optical density of TPH2, SERT and 5HT1A signal in the dorsal raphe nucleus of HSR and SS macaques treated with placebo or citalopram for 15 weeks. For all genes, there was a significant effect of stress sensitivity on optical density and on positive pixel area. However, there was no effect of drug treatment on optical density or on positive pixel area and there was no interaction. From (Lima et al., 2009).

Stress Sensitivity Drug Treatment Interaction
OD Positive pixel area OD Positive pixel area OD Positive pixel area
TPH2 *p=0.0002 *p=0.0003 p=0.13 p= 0.10 p=0.37 p=0.57
SERT *p=0.005 *p=0.001 p=0.27 p= 0.22 p=0.66 p=0.98
5HT1A *p=0.004 *p=0.001 p=0.89 p= 0.83 p=0.17 p=0.072