Table 1.

SNPs in the HNF1B region that were associated with prostate cancer at genome-wide significance levels (P < 5.0 × 10⁻⁸)

SNP	Base pair position	Region	Minor allele	Other allele	Minor allele frequency: cases	Minor allele frequency: controls	No. of cases	No. of controls	OR (95% CI)a	P-value	Heterogeneity P	I2 (%)
rs4430796	33172153	1	G	A	0.420	0.473	10220	9073	0.81 (0.77–0.84)	1.62 × 10−24	0.64	0
rs2005705	33170413	1	T	C	0.394	0.445	10268	9120	0.81 (0.78–0.85)	2.54 × 10−23	0.96	0
rs7405696	33176148	1	C	G	0.485	0.433	10258	9117	1.23 (1.18–1.28)	9.35 × 10−23	0.16	31.5
rs7501939	33175269	1	T	C	0.351	0.394	10247	9100	0.84 (0.80–0.87)	1.22 × 10−16	0.56	0
rs4239217	33173100	1	G	A	0.352	0.395	10266	9120	0.84 (0.80–0.87)	1.57 × 10−16	0.77	0
rs757210	33170628	1	A	G	0.326	0.366	10134	8974	0.84 (0.80–0.88)	1.39 × 10−15	0.95	0
rs3760511	33180426	1	C	A	0.379	0.339	10261	9116	1.19 (1.14–1.24)	4.45 × 10−15	0.33	12.1
rs4794758	33154541	2	T	C	0.247	0.275	10045	8893	0.86 (0.82–0.90)	4.95 × 10−10	0.79	0
rs3744763	33164998	1	C	T	0.383	0.411	10263	9117	0.89 (0.85–0.92)	1.21 × 10−08	0.79	0
rs11649743	33149092	2	A	G	0.176	0.197	10261	9103	0.86 (0.82–0.91)	3.54 × 10−08	0.44	0.1

^aOdds ratio per minor allele.