Table 1.

Clinical characteristics of nonadherent patients with BD

	Frequency, n (%)	Mean (median)	SD	Range
Age		37 (36.5)	12.14	18–59
Sex
Female	14 (70)
Race
Euro-American	4 (20)
African American	14 (70)
American Indian/Native American	1 (5)
Asian	1 (5)
Marital status
Single	13 (65)
Married	1 (5)
Separated	1 (5)
Divorced	5 (25)
Education (y)		13 (12.0)	2.12	9–16
Occupation
Full time	4 (20)
Part time	2 (10)
Unemployed	8 (40)
Other	6 (30)
History of sexual abuse	12 (60)
Substance abuse/dependence (current)^a	9 (45)
Bipolar type
I	13 (65)
II	7 (35)
HAMD-17		19.20 (18.5)	5.1	12–28
YMRS		13.6 (14.5)	7.28	3–35
BPRS		41.2 (40)	8.06	29–60
CGI-BP
Mania		3.8 (4.0)	1.19	2–7
Depression		4.7 (5.0)	0.98	2–7
Overall bipolar illness		4.4 (4.0)	0.59	4–6
AMSQ total		8.3 (8.0)	4.13	2–16
Subscales mean (average per item^b)
Opposition to prophylaxis		1.35 (0.34)	1.35	0–4
Denial of therapeutic effectiveness		0.40 (0.20)	0.68	0–2
Fear of side effects		1.00 (0.50)	0.73	0–2
Difficulty with medication routines		2.65 (0.66)	1.23	0–4
Denial of illness severity		1.65 (0.55)	0.88	0–3
Negative attitude toward drugs in general		0.95 (0.32)	0.76	0–2
Lack of information about mood stabilizers		0.30 (0.30)	0.47	0–1
DAI		4.61 (4.0)	2.78	0–9
Pill count, % missed		40.86%	30.66	7–100
TRQ
Past month		41%	17.84	13–100
Past week		43%	17.43	14–100
ROMI
Adherence		16.25 (16.5)	3.83	5–22
Nonadherence		11.95 (12.5)	3.96	3–21

DAI indicates Drug Attitude Inventory (10-item version, scale calibrated 0–10 with 10 being more positive attitudes); HAMD-17, Hamilton Depression Rating Scale, 17-item version; CGI-BP, Clinical Global Impression for use in Bipolar Disorder; TRQ, Tablets Routine Questionnaire, % of pills missed in last month or week as noted; Pill count, adherence to medication determined by pill count (last month).

As defined by the MINI.

AMSQ subscales have varying numbers of items.