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. Author manuscript; available in PMC: 2011 Jul 21.
Published in final edited form as: Autoimmunity. 2009 Feb;42(2):89–103. doi: 10.1080/08916930802629554

Figure 5.

Figure 5

CSR is significantly upregulated in lupus-prone MRL/faslpr/lpr mice. (a) Cells from spleen, lymph nodes or Peyer’s patches of MRL/faslpr/lpr or non-autoimmune C57BL/6 mice were stained with PE-labeled anti-B220 mAb, and FITC-labeled anti-IgM mAb, the IgM- B220+ cells are considered as switched B cells; (b) Cells from spleen, lymph nodes or Peyer’s patches of MRL/faslpr/lpr or non-autoimmune C57BL/6 mice were stained with PE-labeled anti-B220 mAb, and FITC-labeled anti-IgA mAb; (c) Spleen cells from MRL/faslpr/lpr or non-autoimmune C57BL/6 mice were stained with PE-labeled anti-B220 mAb, and FITC-labeled anti-IgG1, anti-IgG2a, anti-IgG2b, or anti-IgG3 mAb. Stained cells were then analyzed by FACS.