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. Author manuscript; available in PMC: 2011 Nov 27.
Published in final edited form as: Cell. 2011 May 12;145(5):745–757. doi: 10.1016/j.cell.2011.04.022

Figure 2. Maternal transmission of an exacerbated DSS colitis phenotype.

Figure 2

Newborn ASC−/− and WT mice were swapped between their respective mothers (cross-fostered), followed by induction of acute DSS colitis at 8 weeks of age. Body weight and colonoscopy severity score were measured in ASC−/− mice and ASC−/− mice cross-fostered with WT mothers (CF-ASC−/−, A,B); WT mice and WT mice cross-fostered with ASC−/− mothers (CF-WT, C,D); WT mice cohoused with ASC−/− or cross-fostered ASC−/− mice for 4 weeks (E,F). Data are representative of 3 independent experiments. Error bars represent the SEM of samples within a group. *: p<0.05 by One-way ANOVA.