Fig. 2.

Simvastatin did not affect OBX-induced hyperactivity. Rats received daily either simvastatin (10 mg/kg, p.o.) or vehicle for 14 days, starting 48 h post-surgery. Shown is mean + SEM of distance traveled during the first 5 min of the open field test. Post hoc comparisons vs. controls, ***p ≤ 0.001, **p ≤ 0.01. N = 11–13