Fig. 4.

Simvastatin significantly improved object–place recognition selectively for control animals. a Performance in object–location task for control and OBX groups receiving either vehicle or simvastatin. N = 10–11. b Performance for each group in object-in-place task. N = 10–12. Simvastatin (10 mg/kg, p.o.) was administered daily for 25 days. Shown is the mean + SEM of the discrimination ratio in the first minute of the test phase. ***Denotes significant difference from chance (= 0) (one sample t test, p ≤ 0.001)