Table 1. Description and categorization of biological metrics.
Metric Level | Metric | Short Name |
Protein Metrics | Gene Ontology: Molecular Function | F |
Gene Ontology: Biological Process | P | |
Gene Ontology: Cellular Compartment | C | |
Site Metrics | Pfam Domains | Pfam |
Domain Phosphorylation | Pfam Site | |
PhosphoELM Kinase Annotations | PELM Kinase | |
Linear sequences | Motifs | |
Scansite Kinase Predictions | Scansite Kinase | |
Scansite Binding Predictions | Scansite Bind | |
Dynamic Quantitative Metrics | Minimum Phosphorylation | MinValue |
Maximum Phosphorylation | MaxValue | |
Maximum Positive Change | MaxPosChange | |
Maximum Negative Change | MaxNegChange |
There are a total of nine biological metrics and four dynamic metrics analyzed for enrichment in clusters. The metrics tested describe information regarding the protein a peptide arises from, the particular site of phosphorylation, or the quantitative data. The abbreviated labels used throughout this work are given.