Table 1. Univariate Analysis of let-7a Expression and Clinicopathological Risk Factors in Patients with HCC.

		Total	relative let-7 expressiona			rb	P
			≥2	(0.5, 2)	≤0.5
Age (years)	≥55	15	1	8	6	0.193	0.281
	<55	18	5	7	6
Gender	male	29	6	14	9	0.295	0.096
	female	4	0	1	3
Tumor size (cm)	≥5	20	4	11	5	0.142	0.431
	<5	13	2	5	7
Tumor grade	2	6	0	4	2	0.1	0.581
	3	27	6	11	10
HBsAg	(+)	20	3	7	10	0.235	0.189
	(-)	13	3	8	2
Cirrhosis	(+)	22	4	9	9	0.09	0.619
	(-)	11	2	6	3

^aThe let-7a expression of primary HCC tissues relative to normal liver tissues.

^bThe correlation coefficient between types of each clinicopathological risk factors and the three status of let-7a expression (i.e. decreased, increased, or unaltered).