Table 3. HLA-DPB1 allele frequency in pediatric asthma and controls.
| Allele | Asthma | Control 1 | Control 2 | Asthma vs Control 1 | Asthma vs Control 2 | Asthma vs Control 1+2 | |||
| n = 1135 | n = 794 | n = 1475 | P | OR (95%CI) | P | OR (95%CI) | P | OR (95%CI) | |
| DPB1*05:01 | 34.4% | 36.5% | 38.0% | 0.18 | 0.91(0.80–1.04) | 0.007 | 0.85(0.76–0.96) | 0.013 | 0.87(0.79–0.97) |
| DPB1*02:01 | 22.4% | 24.2% | 24.3% | 0.19 | 0.90(0.78–1.05) | 0.11 | 0.89(0.79–1.02) | 0.09 | 0.90(0.80–1.02) |
| DPB1*09:01 | 14.5% | 10.1% | 10.3% | 5.5×10−5 | 1.51(1.23–1.84) | 3.4×10−6 | 1.48(1.25–1.75) | 2.0×10−7 | 1.49(1.28–1.74) |
| DPB1*04:02 | 10.0% | 9.2% | 9.6% | 0.38 | 1.10(0.89–1.37) | 0.57 | 1.05(0.88–1.27) | 0.43 | 1.07(0.90–1.27) |
| DPB1*04:01 | 4.8% | 7.1% | 5.0% | 0.0019 | 0.65(0.50–0.86) | 0.64 | 0.94(0.73–1.21) | 0.08 | 0.82(0.65–1.03) |
| DPB1*03:01 | 4.9% | 4.7% | 4.0% | 0.76 | 1.05(0.78–1.41) | 0.11 | 1.24(0.95–1.62) | 0.21 | 1.17(0.92–1.48) |
| DPB1*02:02 | 3.7% | 3.2% | 3.4% | 0.46 | 1.14(0.80–1.63) | 0.61 | 1.08(0.80–1.45) | 0.49 | 1.10(0.84–1.45) |
| DPB1*13:01 | 1.6% | 1.5% | 2.1% | 0.85 | 1.05(0.62–1.77) | 0.18 | 0.75(0.50–1.14) | 0.38 | 0.84(0.57–1.24) |
| DPB1*14:01 | 1.8% | 1.7% | 1.4% | 0.88 | 1.04(0.63–1.70) | 0.258 | 1.28(0.83–2.01) | 0.39 | 1.19(0.80–1.76) |