Figure 2. Myeloid IκBα deficiency promotes atherosclerosis in ldlr ^−/− mice.

Representative pictures of toluidine blue-stained sections in the aortic root of (A) IκBα^WT or (B) myeloid-specific IκBα^del mice, original magnification ×40. (C) Lesion area in the aortic root of IκBα^WT and IκBα^del mice (** p<0.01; n = 18/16). (D) Lesion severity in the aortic root of IκBα^WT and IκBα^del mice (Chi square test; *** p<0.0001; n = 54/48) was typed as absent (0), early (1+2), or advanced (4+5), as described before [15].