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. 2011 Jul 21;6(7):e22434. doi: 10.1371/journal.pone.0022434

Figure 5. B cell activation in the spleen of P. chabaudi-infected WT, CD1d-/- and I-Ab-/- mice.

Figure 5

(A) Numbers of B220+ cells per spleen on days 0, 4 and 7 of infection. Data represent the means ± SD (n = 6–9). (B) Histograms showing CD69 expression in gated B220+ cells on days 0 and 7 of infection. Numbers in histograms represent the means ± SD (n = 4–6) of MFI values. (C) Dot plots showing MZ (CD21highCD23lowB220+) B cells and FO (CD21lowCD23highB220+) B cells on days 0 and 7 of infection. Numbers in dot plots represent the means ± SD (n = 4–7) of the percentages of each subpopulation. (D) Histograms showing CD1d and CD69 expression in gated MZ and FO B cells on days 0 and 7 of infection. Numbers in histograms represent the means ± SD (n = 4–7) of MFI values. In A-D, *, p<0.05, infected mice compared with non-infected mice; ε, p<0.05, CD1d-/- or I-Ab-/- mice compared with WT mice. Data are representative of three experiments.