Figure 2. Body weight during and after tamoxifen diet administration in Vhl^floxed-UBC-Cre-ER^T2 and control mice.

Body weight of Vhl^wt-UBC-Cre-ER^T2 (n = 3), Vhl^floxed-UBC-Cre-ER^T2 (n = 6) control Vhl^floxed (n = 6) mice was measured before tamoxifen treatment (TFX 0d), at the end of 10 days on a tamoxifen diet (TFX 10d) and one day after returning to a normal diet (N +1d). Statistical significance was assessed using a two-tailed Student's t-test, (*, p<0.05; **, p<0.01; ns, no significant differences).