Table 1.

Basic physiological and metabolic parameters of control and high fat diet mice.

Variable	Control Diet	Control Diet + Leptin 10 μg/day	Control Diet + Leptin 40 μg/day	High Fat Diet	High Fat Diet + Leptin 10 μg/day	High Fat Diet + Leptin 40 μg/day
Body Weight (g)	34.5±0.5	*31.2±0.8	*29.4±0.6	†47.7±1.5	†46.4±0.8	†49.0±2.1
Glycemia (mg/dL)	141±13	121±7	123±8	*203±19	*166±8	*197±14
Hb1Ac	4.8±0.1	4.6±0.1	4.9±0.1	*5.7±0.2	*5.6±0.1	*5.4±0.1
Insulin (μg/mL)	61.4±4.0	48.6±8.4	*33.3±7.0	*603.8±278.5	*398.8±145.3	*419.1±52.3
Cholesterol (mg/dL)	56.5±7.5	*50.4±7.0	87.4±5.9	†93.3±12	*84.8±7.35	180.9±13.1
Triglycerides (mg/dL)	37.6±8.2	26.1±0.9	36.6±3.0	38.7±8.9	35.9±5.7	58.2±8.02

Data are presented as mean ± sem,

^*p<0.05 vs control diet,

^†p<0.0001 vs. control diet,

^#p<0.05 vs control condition within the same group, n=10–12 per group.