Table 2.
Full output from interval-censored parametric survival analysis showing the effect of community-level mean lifetime partners and prevalence of partnership concurrency in men on a woman's hazard of acquiring HIV infection (N=7284)
|
Mean lifetime partners* |
Concurrency* |
Both† |
||||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | HR (95% CI) | p value | |||
| Unadjusted models | ||||||||
| Mean lifetime partners | 1·09 (1·03–1·14) | 0·001 | .. | .. | 1·10 (1·04–1·16) | 0·001 | ||
| Concurrency (10% increase) | .. | .. | 1·00 (0·94–1·07) | 0·981 | 0·96 (0·90–1·03) | 0·307 | ||
| Adjusted models | ||||||||
| Community level (male) | ||||||||
| Mean lifetime partners | 1·08 (1·03–1·14) | 0·004 | .. | .. | 1·09 (1·03–1·15) | 0·004 | ||
| Concurrency (10% increase) | .. | .. | 1·02 (0·95–1·09) | 0·556 | 0·99 (0·91–1·06) | 0·730 | ||
| Prevalence (10% increase)*‡ | 1·17 (0·98–1·39) | 0·074 | 1·20 (1·01–1·42) | 0·042 | 1·17 (0·99–1·39) | 0·072 | ||
| Individual level | ||||||||
| Partners in previous 12 months (vs 0) | ||||||||
| One | 2·58 (1·43–4·64) | 0·002 | 2·56 (1·42–4·62) | 0·002 | 2·58 (1·43–4·64) | 0·002 | ||
| More than one | 4·84 (2·45–9·56) | <0·0001 | 4·84 (2·45–9·56) | <0·0001 | 4·83 (2·45–9·54) | <0·0001 | ||
| Marital status (vs single) | ||||||||
| Married, monogamous | 0·60 (0·43–0·83) | 0·002 | 0·60 (0·44–0·84) | 0·002 | 0·60 (0·44–0·84) | 0·002 | ||
| Married, polygamous | 0·67 (0·34–1·33) | 0·250 | 0·67 (0·34–1·34) | 0·257 | 0·67 (0·34–1·33) | 0·250 | ||
| Urban (vs rural) | ||||||||
| Peri-urban | 1·17 (0·95–1·45) | 0·147 | 1·19 (0·96–1·47) | 0·118 | 1·16 (0·94–1·44) | 0·166 | ||
| Urban | 0·71 (0·31–1·63) | 0·418 | 0·72 (0·31–1·66) | 0·444 | 0·71 (0·31–1·63) | 0·415 | ||
| Wealth tertile (vs wealthiest) | ||||||||
| Intermediary wealth | 0·94 (0·76–1·15) | 0·553 | 0·94 (0·77–1·16) | 0·581 | 0·94 (0·76–1·15) | 0·551 | ||
| Poorest | 0·87 (0·70–1·09) | 0·220 | 0·89 (0·71–1·10) | 0·283 | 0·87 (0·70–1·08) | 0·217 | ||
| Years of education | 0·96 (0·93–0·98) | 0·001 | 0·96 (0·93–0·98) | 0·001 | 0·96 (0·93–0·98) | 0·001 | ||
| Age (vs 15–19 years) | ||||||||
| 20–24 years | 1·52 (1·25–1·84) | <0·0001 | 1·50 (1·24–1·82) | <0·0001 | 1·52 (1·25–1·84) | <0·0001 | ||
| 25–29 years | 1·11 (0·82–1·49) | 0·498 | 1·10 (0·82–1·47) | 0·539 | 1·11 (0·82–1·49) | 0·499 | ||
| 30–34 years | 0·72 (0·50–1·03) | 0·069 | 0·71 (0·49–1·01) | 0·057 | 0·72 (0·50–1·03) | 0·069 | ||
| 35–39 years | 0·55 (0·39–0·79) | 0·001 | 0·55 (0·38–0·79) | 0·001 | 0·55 (0·39–0·79) | 0·001 | ||
| 40–44 years | 0·29 (0·19–0·44) | <0·0001 | 0·29 (0·19–0·44) | <0·0001 | 0·29 (0·19–0·44) | <0·0001 | ||
| ≥45 years | 0·19 (0·12–0·28) | <0·0001 | 0·19 (0·12–0·28) | <0·0001 | 0·19 (0·12–0·28) | <0·0001 | ||
HR=hazard ratio.
Derived from male sexual behaviour in the surrounding local community with a standard Gaussian kernel (radius 3 km) around each woman in the cohort (figure 2).
Includes both male community-level mean lifetime partners and prevalence of concurrent partnerships covariates.
Unadjusted hazard ratio, 1·26 (p<0·0001).