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. 2011 Mar 30;39(13):5757–5767. doi: 10.1093/nar/gkr146

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© The Author(s) 2011. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Summary of current interpretation of the DNA-PK system. (A) Ku70:80 views, current study. The feature of the bridge in the Ku dimer is highlighted with a white arrow. (B) Ku70:80 views (31). (C) DNA-PKcs views, current study. (D) DNA-PKcs views (26). (E) DNA-PK views, current study. (F) DNA-PK views (9). In E and F, the density relative to Ku in the DNA-PK complex is highlighted with a white arrow. (G) Dephosphorylated DNA-PK dimer views (9). (H) Dephosphorylated DNA-PK dimer views obtained by classification with a local mask on the upper subunit, current study. (I) Autophosphorylated DNA-PK dimer views. (J) Autophosphorylated DNA-PK dimer views obtained by classification with a local mask, current study. The white arrows point to the Ku density. Box size = 560 Å.