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. 2011 May 4;39(13):e87. doi: 10.1093/nar/gkr251

Figure 4.

Figure 4.

Applications of NOA on yeast TF co-regulatory networks. (A) NOA results on the yeast TF co-regulatory network in response to cell-cycle condition. (A1) illustrates the TF co-regulatory network. We construct TF co-regulatory networks by defining the TF co-regulation relationship if two TFs regulate at least one common target. (A2, A3) shows the comparison between NOA and gene list methods (GLM). (A2) presents the rank of all related GO terms in the four methods. Pink part represents significant terms with P-value less than 0.05, and the position of GO:0022402 (cell-cycle process) is shown by a red horizontal bar. (A3) shows P-values of GO:0022402 reported by the four methods. (B) NOA results on the yeast TF co-regulatory network in response to sporulation condition. (B2) The position of GO:0043934 (sporulation) is shown by a blue horizontal bar. (B3) shows P-values of GO:0043934 reported by four methods. The red dash line is the base line of –log(0.05).