Table 4.

Comparison of DC Patients with Pulmonary Disease with and without HSCT*

Parameter	HSCT	No HSCT	**P value
Number with pulmonary disease/total number***	12/70	37/488	0.03
Odds Ratio for pulmonary disease vs. no pulmonary disease, in patients with HSCT	2.2 (1-4.5)	-	0.03
Age (years) at pulmonary disease in those who developed pulmonary disease, median (range)	14 (4-36)	37 (7-68)	<0.001
Median survival age (years) free of pulmonary disease	34	61	<0.001
Interval (years) from HSCT to pulmonary disease, median (range)	4.5 (0-20)	-	-
Number who died	9/12	24/37	0.8
Interval (years) from pulmonary disease to death in those who developed pulmonary disease, median (range)	0.3 (0-2)	0 (0-8)	0.5
Median survival interval (years) after pulmonary disease,	1	2	0.3

* Data obtained from the cases in Tables 2 and 3.

**P values compare the patients who received HSCT with those who did not receive HSCT.

*** The denominator is the total number of patients with DC who did or did not receive HSCT.

Abbreviations: DC, dyskeratosis congenita; HSCT, hematopoietic stem cell transplantation.