Figure 2.

Western blot showing that intrathecal lidocaine pretreatment decreased Nav_1.3 up-regulation in injured DRGs after SNL (A). Quantification of Nav_1.3 band densities showed Nav_1.3 expression was up-regulated after SNL, but was decreased on POD₃ in Group P (C). Western blot and quantification of Nav_1.8 band densities showing that intrathecal lidocaine pretreatment did not reduce Nav_1.8 down-regulation in Group P (B, D). (*p < 0.05, **p < 0.01, ☆P <0.001, NS: not statistically significant; ANOVA with post hoc Scheffe's test.)