Table 3.
mRNA expression of MMPs and inhibitors in control mammary glands and benign and malignant mammary tumors.
| Gene | mRNA expression -fold changes (arbitrary units) |
||
|---|---|---|---|
| Control mammary gland | Benign tumors | Malignant tumors | |
| MMP-2 | 1.00 ± 0.46 | 1.01 ± 0.18 | 0.76 ± 0.12 |
| MMP-9 | 1.00 ± 0.30 | 9.95 ± 4.40 | 7.23 ± 1.58 |
| MMP-13 | 1.00 ± 0.28 | 2.08 ± 0.70 | 1.27 ± 0.25 |
| MT1-MMP | 1.00 ± 0.24 | 13.26 ± 6.09 | 2.82 ± 0.64 |
| TIMP-1 | 1.00 ± 0.17 | 4.96 ± 1.27 | 3.97 ± 0.66 |
| TIMP-2 | 1.00 ± 0.34 | 0.49 ± 0.09 | 0.60 ± 0.09 |
| TIMP-3 | 1.00 ± 0.35 | 4.16 ± 1.62 | 2.38 ± 0.65 |
| RECK | 1.00 ± 0.52 | 3.41 ± 1.77 | 0.51 ± 0.10 |
Data are expressed as the mean ± SEM.