Table 5.
Immunohistochemical score for epithelial tumor cells and fibroblasts in benign and malignant mammary tumors, expressed as the average percentage from ten fields.
| Protein | Cell type | Immunohistochemical score (%) | p value | |
|---|---|---|---|---|
| Benign tumors | Malignant tumors | |||
| MMP-2 | Tumor cells | 88.6 | 67.5 | 0.05 |
| Fibroblasts | 11.4 | 32.5 | ||
| MMP-9 | Tumor cells | 84.1 | 89.4 | 0.002 |
| Fibroblasts | 15.9 | 10.6 | ||
| MMP-13 | Tumor cells | 56.4 | 65.9 | n.s. |
| Fibroblasts | 43.6 | 34.1 | ||
| MT1-MMP | Tumor cells | 80.3 | 55.8 | 0.001 |
| Fibroblasts | 19.7 | 44.2 | ||
| TIMP-2 | Tumor cells | 53.3 | 79.6 | n.s. |
| Fibroblasts | 46.7 | 20.4 | ||
n.s. = not significant