Table 1.
Sampling schedule for ECUAVIDA cohort
| Visit | Ante-natal | Birth | < 2 wks | 3 mths | 7 mths | 13 mths | 24 mths | 3 years | 5 yrs | 8 yrs |
|---|---|---|---|---|---|---|---|---|---|---|
| Site | HPAB | HPAB | Home | HPAB/home | HPAB/home | Home | HPAB/home | HPAB/home | HPAB/home | Home |
| Child | ||||||||||
| Questionnaire | X | X | X | X | X | X | X | X | ||
| Faeces | X | X | X | X | X | X | X | X | X | |
| Blood | Xa | X | X | X | X | X | X | X | ||
| Clinical exam | X | X | X | X | X | X | X | X | ||
| Anthropometry | X | X | X | X | X | X | ||||
| SPT | X | X | X | X | ||||||
| PFTs/BHR | X | |||||||||
| Mantoux test | X | |||||||||
| Mother | ||||||||||
| Questionnaire | X | X | X | X | ||||||
| Faeces | X | X | X | |||||||
| Blood | X | |||||||||
| SPT | ||||||||||
| Father | ||||||||||
| Faeces | X | X | ||||||||
| SPT | ||||||||||
| Household | ||||||||||
| GPS | Xb | Xb | ||||||||
| Dust | Xb | |||||||||
| Faeces | X | |||||||||
Stool samples are collected also at 18 and 30 months. HPAB-Hospital Padre Alberto Buffoni in Quinindé, Esmeraldas Province; SPT-allergen skin test reactivity; PFTs-pulmonary function tests measured by spirometry; BHR-bronchial hyperresponsiveness or evidence of reversibility following β2 agonist; GPS-geographic positioning system measurements for mapping of households. a immunology sub-cohort only. b measurements repeated for change of address.