Table 3.
The association of IL8 SNPs with the risk of idiopathic pulmonary fibrosis (IPF) by gender
Male | Female | ||||||
MAF | OR(95%CI)* | P* | MAF | OR(95%CI)* | P* | ||
IPF and Clinical IPF (n = 152) | NC (n = 178) | IPF and Clinical IPF (n = 70) | NC (n = 276) | ||||
0.340 | 0.394 | 0.51 (0.26-0.97) | 0.04 | 0.331 | 0.351 | 0.53 (0.18-1.57) | 0.25 |
0.336 | 0.394 | 0.49 (0.26-0.93) | 0.03 | 0.336 | 0.350 | 0.57 (0.20-1.64) | 0.30 |
0.288 | 0.326 | 0.83 (0.39-1.75) | 0.62 | 0.316 | 0.297 | 0.64 (0.19-2.24) | 0.49 |
0.064 | 0.071 | . | . | 0.008 | 0.054 | . | . |
* Logistic models were used for calculating odd ration and p-values in recessive model controlling for age, sex, and smoking status as covariates.
NC: normal controls
MAF: Minor allele frequency