Table 4.
Genes with at least one significant probe per gene in the human data and at least in one mouse data set (adjusted p-value <0.05)
| Human gene symbol | Mouse gene symbol | Beta coef.* human | Beta coef.* A/J | Beta coef.* SW | Beta coef.* C57BL6 | p-value human data* | p-value A/J† | p-value SW† | p-value C57BL6† | Combined p-value‡ |
|---|---|---|---|---|---|---|---|---|---|---|
| NOD1 | Nod1 | 0.012 | - | - | 0.133 | 7.0E-8 | - | - | 2.1E-2 | 4.7E-9 |
| EDN1 | Edn1 | 0.026 | 0.018 | 0.054 | 0.138 | 1.6E-6 | 7.4E-3 | 1.4E-3 | 2.4E-2 | 3.9E-11 |
| ROBO1 | Robo1 | -0.009 | -0.014 | - | -0.055 | 1.5E-5 | 3.8E-2 | - | 9.4E-2 | 6.9E-7 |
| IL4R | Il4ra | 0.01 | 0.033 | 0.032 | 0.1 | 3.4E-5 | 3.0E-5 | 2.3E-2 | 5.5E-2 | 5.8E-11 |
| RORA | Rora | 0.022 | 0.01 | 0.025 | 0.107 | 3.5E-5 | 1.3E-2 | 9.2E-3 | 2.1E-2 | 5.5E-9 |
| PLAUR | Plaur | -0.008 | 0.013 | 0.015 | 0.106 | 2.0E-4 | 2.3E-2 | 5.2E-2 | 2.1E-2 | 9.8E-1 |
| CCL5 | Ccl5 | 0.008 | 0.022 | 0.027 | 0.079 | 2.6E-4 | 1.6E-7 | 1.9E-3 | 2.0E-2 | 5.5E-13 |
| IRAK3 | Irak3 | -0.011 | - | - | 0.073 | 1.3E-3 | - | - | 4.5E-2 | 2.0E-2 |
| IL18 | Il18 | 0.004 | 0.01 | 0.018 | 0.139 | 1.6E-3 | 4.4E-4 | 2.4E-2 | 2.7E-1 | 1.3E-7 |
| STAT6 | Stat6 | 0.007 | 0.021 | 0.002 | 0.106 | 1.8E-3 | 1.6E-2 | 6.0E-1 | 4.7E-2 | 2.5E-5 |
| CHIA | Chia | 0.009 | 0.077 | 0.039 | 0.288 | 1.8E-3 | 5.7E-3 | 3.4E-1 | 3.3E-2 | 4.0E-6 |
| HLA-G | H2-M3 | 0.01 | 0.021 | 0.032 | 0.103 | 2.6E-3 | 2.9E-5 | 9.2E-4 | 1.7E-2 | 3.7E-10 |
| CD86 | Cd86 | 0.003 | 0.001 | 0.008 | 0.097 | 5.6E-3 | 9.3E-1 | 1.3E-1 | 3.1E-2 | 1.9E-3 |
| PRNP | Prnp | -0.003 | 0.02 | 0.031 | 0.106 | 8.9E-3 | 8.8E-3 | 1.1E-1 | 7.2E-2 | 5.0E-1 |
| PCDH1 | Pcdh1 | 0.006 | - | - | 0.232 | 1.0E-2 | - | - | 3.1E-2 | 1.6E-3 |
| SERPINE1 | Serpine1 | 0.021 | 0.018 | 0.02 | 0.129 | 1.6E-2 | 4.5E-5 | 9.6E-3 | 1.7E-2 | 3.3E-8 |
| TNF | Tnf | 0.004 | -0.003 | 0.007 | 0.051 | 2.3E-2 | 3.7E-1 | 2.6E-1 | 4.9E-2 | 4.5E-2 |
| TLE4 | Tle4 | -0.004 | -0.009 | 0.006 | -0.07 | 2.3E-2 | 1.0E-3 | 3.1E-1 | 3.0E-1 | 1.0E-3 |
| SCGB1A1 | Scgb1a1 | 0.017 | 0.163 | 0.09 | 0.736 | 3.8E-2 | 1.2E-3 | 5.1E-2 | 1.8E-2 | 4.6E-6 |
* The beta coefficient corresponds to the mean change in gene expression per day during the studied period.
† Adjusted p-value (B-H method). ‡ Combined p-value for all data sets (human and murine) using the weighted z-score method.
Empty boxes (-) indicate that the gene was not represented on the chip. Bolded rows indicate genes with at least one significant probe per gene in all tested data sets (adjusted p-value <0.05).