Table 2.
Daily flow chart summarising PN administration (maximum possible) and data collection
| PN administration (macronutrient content) | Week | Data collection (nutrition) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (d) | Protein (g) | Lipid (g) | Dextrose; PN (%) | Dextrose; Suppl (%) | 1 | Enteral/IV fluid intake (ICR) | U/EBG | Bone/LFT | TG | AA | Growth | ||||
| std | max | std | max | std | max | std | max | PN type | |||||||
| 1 | 1.8 | 1.8 | 1.0 | 1.0 | 10 | 10 | 10 | 10 | PN | • | • | • | |||
| 2 | 1.8 | 1.8 | 1.0 | 1.0 | 10 | 10 | 10 | 10 | Consent & | • | • | • | |||
| 3 | 2.4 | 2.9 | 1.9 | 1.9 | 10 | 12 | 10 | 12 | randomise | • | • | • | |||
| 4 | 2.4 | 2.9 | 1.9 | 1.9 | 10 | 12 | 10 | 12 | • | • | • | ||||
| 5 | 2.8 | 3.8 | 2.8 | 2.8 | 10 | 12 | 10 | 12 | • | • | |||||
| 6 | 2.8 | 3.8 | 2.8 | 2.8 | 10 | 12 | 10 | 12 | SCAMP | • | • | • | |||
| 7 | 2.8 | 3.8 | 2.8 | 3.8 | 10 | 12 | 10 | 12 | SCAMP | • | • | • | • | ||
| PN administration (macronutrient content) | Week | Data collection (nutrition) | |||||||||||||
| Age (d) | Protein (g) | Lipid (g) | Dextrose; PN (%) | Dextrose; Suppl (%) | 2-4 | Enteral/IV fluid intake (ICR) | U/EBG | Bone/LFT | TG | AA | Growth | ||||
| std | max | std | max | std | max | std | max | PN type | |||||||
| 8 | 2.8 | 3.8 | 2.8 | 3.8 | 10 | 12 | 10 | 12 | SCAMP | • | • | • | |||
| 9 | 2.8 | 3.8 | 2.8 | 3.8 | 10 | 12 | 10 | 12 | SCAMP | • | • | • | |||
| 10 | 2.8 | 3.8 | 2.8 | 3.8 | 10 | 12 | 10 | 12 | SCAMP | • | • | ||||
| 11 | 2.8 | 3.8 | 2.8 | 3.8 | 10 | 12 | 10 | 12 | SCAMP | • | • | • | |||
| 12 | 2.8 | 3.8 | 2.8 | 3.8 | 10 | 12 | 10 | 12 | SCAMP | • | • | ||||
| 13 | 2.8 | 3.8 | 2.8 | 3.8 | 10 | 12 | 10 | 12 | SCAMP | • | • | • | |||
| 14 | 2.8 | 3.8 | 2.8 | 3.8 | 10 | 12 | 10 | 12 | SCAMP | • | • | • | • | ||
Legend: Daily flow chart summary of SCAMP nutrition study protocol including consent, randomisation, PN administration and data collection. Week 2 flow chart is repeated in week 3 and 4 to complete the 28 day intervention period. Day 29: Patient reverts to standard PN (if still on PN). All routine data collection stops apart from routine weekly growth data which continues until 36 weeks corrected for gestational age.
Abbreviations: stnd: standard PN (scNPN); max: scNPNmax; ICR: intensive care record of daily fluid/nutrient/drug administration; U/E, BG: routine biochemical monitoring of plasma electrolytes, glucose, lactate and blood gases; Bone/LFT: routine biochemical monitoring of plasma bone and liver biochemistry; TG: triglyceride levels; AA amino acid levels.