Table 3.
Statistical correlation of disease characteristics with survival outcomes
| Characteristic (%) | Median OS (y) | p | Median RFS (y) | p |
|---|---|---|---|---|
| IORT dose | 0.863 | 0.029 | ||
| ≤ 1500 cGy (39.1%) | 1.2 | 1.5 | ||
| > 1500 cGy (60.9%) | 1.5 | NE | ||
| Energy | 0.064 | 0.006 | ||
| 4 MeV (29%) | 1.0 | NE | ||
| 5 MeV (51%) | 1.6 | NE | ||
| 6+ MeV (20%) | 1.0 | 0.8 | ||
| ECE | 0.569 | 0.310 | ||
| Yes (12%) | 1.4 | 0.9 | ||
| No (88%) | 1.7 | 3.9 | ||
| LVI/AVI | 0.071 | 0.064 | ||
| Yes (16%) | 0.8 | 0.7 | ||
| No (84%) | 1.7 | 3.9 | ||
| PNI | < 0.001 | 0.387 | ||
| Yes (17%) | 0.6 | 1.1 | ||
| No (83%) | 1.9 | 3.9 | ||
| Dermal Invasion | 0.035 | 0.911 | ||
| Yes (21%) | 0.9 | NE | ||
| No (79%) | 1.9 | 3.1 | ||
| Carotid Involvement | 0.010 | 0.199 | ||
| Yes (33%) | 1.0 | 1.1 | ||
| No (67%) | 2.2 | NE | ||
| Vasc. Complications | 0.823 | 0.894 | ||
| Yes (11%) | 1.2 | 1.1 | ||
| No (89%) | 1.2 | 1.5 | ||
| Prior RT | 0.263 | 0.246 | ||
| Yes (81%) | 1.4 | 3.2 | ||
| No (19%) | 2.2 | NE | ||
| Previous Chemo | 0.419 | 0.045 | ||
| Yes (51%) | 1.6 | 1.2 | ||
| No (49%) | 0.9 | 10.4 | ||
| Post Surgery RT | 0.457 | 0.127 | ||
| No (76%) | 1.5 | 10.4 | ||
| Yes (24%) | 1.6 | 1.2 |
Survival times estimated using Kaplan-Meier method and tested between groups using the long-rank test.
NE - not estimable