Table 1.
Study schedule
| Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | |
|---|---|---|---|---|---|---|---|
| Eligibility assessed by paramedic from routine clinical data | x | ||||||
| Study discussed and verbal informed consent/assent obtained by paramedic | x | ||||||
| Randomisation | x | ||||||
| Further study information provided and written informed consent/assent obtained by hospital research team | x | ||||||
| Appropriateness to continue study medication reviewed by hospital team | x | ||||||
| Review of medical records to collect baseline stroke details and medical history | X | ||||||
| Blood pressure measurements | x | x | x | x | |||
| National Institute of Health Stroke Scale | x | x | x | ||||
| Barthel ADL Index (pre-stroke) |
x | ||||||
| Barthel ADL Index (post-stroke) |
x | ||||||
| Modified Rankin Scale (pre-stroke) |
x | ||||||
| Modified Rankin Scale (post-stroke) |
x | ||||||
| Blood test for renal function | x | ||||||
| Review of medical records to record concomitant blood pressure medications | x | ||||||
| Treatment with study medication | x | x | x | x | x | x | x |
| Review of study medication dosage | x | ||||||
| Adverse Events | x | x | x | x | x | x | x |