Table 8.
Age adjusted odds ratio (OR) and 95% confidence interval (CI) for invasive cervical carcinoma according to HIV serology and CD4 count among women who are infected with high-risk human papillomavirus (HPV) typesa
Controls | Squamous cell carcinoma | Adenocarcinoma | |||||
---|---|---|---|---|---|---|---|
Number | Number | OR | 95% CI | Number | OR | 95% CI | |
HIV | |||||||
Any (+or-) | 54 | 183 | 26 | ||||
Negative | 35 | 142 | 1.0 (ref) | 24 | 1.0 (ref) | ||
Positive | 19 | 41 | 0.7 | 0.3-1.4 | 2 | 0.2 | 0.04-0.8 |
CD4 count | |||||||
Any | 37 | 135 | 21 | ||||
>300 | 33 | 113 | 1.0 (ref) | 19 | 1.0 (ref) | ||
≤300 | 4 | 22 | 1.8 | 0.6-6.2 | 2 | 1.8 | 0.3-10.1 |
>500 | 26 | 90 | 1.0 (ref) | 15 | 1.0 (ref) | ||
≤500 | 11 | 45 | 1.4 | 0.6-3.3 | 6 | 0.9 | 0.3-3.1 |
aHigh-risk HPV: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 73.
NOTE: CD4 count classified according to two different cut-points: 300 and 500 cells.