Table 2.
Effects of implantation strategy on clinical outcomes
Cardiovascular death | Cardiovascular death / hospitalizations for HF | Death from any cause / hospitalizations for MACE | ||||
---|---|---|---|---|---|---|
HR (95% CI) * | p | HR (95% CI) * | p | HR (95% CI) * | p | |
+CMR+S | 6.34 (3.64 to 11.0) | < 0.0001 | 5.57 (3.40 to 9.14) | < 0.0001 | 4.74 (2.95 to 7.62) | < 0.0001 |
-CMR | 1.51 (0.96 to 2.36) | 0.0726 | 1.61 (1.09 to 2.38) | 0.0169 | 1.87 (1.31 to 2.66) | 0.0005 |
*, Hazard ratios (HR) and 95% confidence intervals (CI) refer to the risk of meeting the endpoints in comparison to the group in which CMR was performed and the LV lead was deployed in non-scarred myocardium. Adjustment has been made for age, NYHA class, QRS duration, history of CABG and of chronic atrial fibrillation in Cox proportional hazards analyses. +CMR+S = CMR showing scar at the LV pacing position; -CMR = non-CMR guided group.