Table 2. Constitutive activation of kinases in different constitutive mutant clones.
Mutant cell line | IKK | JNK | Akt | p90rsk1 | ERK |
---|---|---|---|---|---|
Z12 | ↑ | ↑ | ↑ | ↑ | ↑ |
Z2 | — | — | ↑ | — | — |
Z3 | — | — | ↑ | ↑ | ↑ |
Z13 | — | — | — | ↑ | ↑ |
P2Z1, P1Z1, Z5, Z23 | — | — | — | — | — |
A dash indicates that the kinase was not constitutively active. JNK, c-Jun N-terminal kinase.