Table 1.
Growth inhibition effect of various constituents of D. versipellis on different cells
| Compound (20 μM) | Growth inhibition (%) | |||
|---|---|---|---|---|
| PC3 | Bcap-37 | BGC-823 | NIT3T3 | |
| β-sitosterol | 14.7 ± 8.5 | 10.9 ± 10.4 | 19.5 ± 9.3 | 1.7 ± 9.3 |
| 4'-demethylpodophyllotoxin | 60.5 ± 5.2** | 56.7 ± 9.1** | 56.9 ± 12.4 | 60.1 ± 6.1** |
| Kaempferol | 43.9 ± 11.9** | 53.2 ± 10.9** | 53.4 ± 14.9 | 39.2 ± 8.2** |
| picropodophyllotoxin-4-O-glucoside | 9.0 ± 9.9 | 7.4 ± 9.3 | 24.6 ± 11.3** | 6.4 ± 8.8 |
| kaempferol-3-O-β-D-glucopyranoside | 23.0 ± 6.4** | 29.9 ± 10.8** | 13.2 ± 8.7 | 23.0 ± 7.9** |
| 4'-demethylpodophyllotoxin-4-O-glucoside | 19.8 ± 7.1** | 21.9 ± 6.5** | 14.5 ± 8.0 | 6.5 ± 7.7 |
| quercetin-3-O-β-D-glucopyranoside | 11.6 ± 9.1 | 15.2 ± 10.1 | 40.7 ± 11.9** | 5.1 ± 9.9 |
| icropodophyllotoxin-4-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside. | 10.2 ± 8.1 | 23.9 ± 10.2 | 23.6 ± 10.7** | 2.2 ± 8.8 |
| Quercetin | 29.8 ± 8.3 | 39.0 ± 13.3** | 22.1 ± 4.3* | 8.1 ± 5.0 |
| Podophyllotoxone | 52.0 ± 5.6** | 42.1 ± 6.3** | 47.9 ± 8.1 | 43.7 ± 6.2** |
| vanillic acid | 29.2 ± 3.9** | 30.3 ± 10.9** | 28.5 ± 12.3 | 10.2 ± 5.0* |
| 4'-demethyldeoxypodophyllotoxin | 67.1 ± 3.4** | 56.6 ± 12.3** | 60.7 ± 9.8** | 59.8 ± 3.5** |
| ADM | 93.2 ± 1.6 | 90.6 ± 1.2** | 98.3 ± 4.0** | 97.5 ± 1.7** |
All the values are expressed as mean ± SD (n = 6). * P < 0.05, ** P < 0.01 compared with control.