Table 4.
Effect of integrated school based de-worming and prompt malaria treatment on helminths -Plasmodium co-infections among 420 primary schoolchildren successfully followed up over 33 months in Burma Valley farming area, Zimbabwe
| Co-infection combinations | Prevalence (95%CI) | ||||
|---|---|---|---|---|---|
| Baseline | 6 months | 12 months | 33 months | Overall (%) reduction | |
| Not infected | 21.4 (17.6-26.7) | 65.2 (60.5-69.8) | 70.0 (65.4-74.3) | 49.0 (44.2-53.9) | - |
| Schistosomiasis | 31.7 (27.2-36.4) | 5.5 (3.5-8.1) | 11.0 (8.1-14.3) | 27.6 (23.4-32.2) | 3.9 |
| STHs | 5.7 (3.7-8.4) | 5.5 (3.5-8.1) | 3.6 (2.0-5.8) | 4.5 (2.7-7.0) | 6.3 |
| P. f | 8.1 (5.7-11.1) | 10.5 (7.7-13.8) | 9.0 (6.5-12.2) | 4.0 (2.4-6.4) | 40.9 |
| Schisto + STHs | 12.9 (9.8-16.4) | 3.6 (2.0-5.8) | 3.8 (2.2-6.1) | 10.7 (7.9-14.1) | 17.1 |
| P. f + schisto | 13.1 (10.0-16.7) | 1.2 (0.4-2.8) | 1.9 (0.8-3.7) | 2.6 (1.3-4.6) | 73.7 |
| P. f + STHs | 1.4 (0.5-3.1) | 1.0 (0.3-2.4) | 0.2 (0.0-1.3) | 0.5 (0.1-1.7) | 63.6 |
| P. f + STHs + schisto | 5.7 (3.7-8.4) | 0.2 (0.0-1.3) | 0.5 (0.0-1.7) | 1.0 (0.3-2.4) | 76.4 |
The rural area was left out in this analysis because there were no mixed infections observed over the period of the study.
Key: Schisto = schistosomiasis, P. f = P. falciparum, STHs = soil transmitted helminths